Animal models have been been indispensable in medical research in enhancing an understanding of how diseases develop and progress and in formulating and testing drugs. But their utility may be coming to an end. Mice are not men and cannot serve as accurate models of complex human conditions like mental illnesses. China has used gene-edited monkeys to serve as disease models and has gone on to clone the mutant monkeys so researchers can work with genetically identical populations. They intend to create more to simulate a variety of different conditions. The article will engage and inform anyone concerned with the ethics of cutting-edge science and medicine.
In this summary, you will learn
- How mouse models of disease have reached their limits;
- Why China is developing populations of cloned, mutated monkeys; and
- Why some researchers have ethical concerns with it.
About the Author
David Cyranoski is the Asia-Pacific correspondent for Nature magazine.