Dengue fever has no vaccine or effective treatment, and it kills some 22,000 people per year. That’s twice the number of people killed by the Ebola virus over the course of 24 outbreaks in close to 40 years. People are, however, obsessed with Ebola, in part because it leads inevitably to a gruesome death. That a vaccine for Ebola has only gone into clinical trials recently speaks to a problem with the development of vaccines for infectious diseases: People vulnerable to such diseases simply can’t pay for the development of the vaccine. Epidemiologist Seth Berkley’s talk offers insight into how to develop vaccines when and where they are most needed.