In: Science
Genetics
Gregor Mendel was fascinated by heredity in organisms. And his studies of genetic variation delivered the very first deep insights. Today, new tools allow the modification of genes, virtually without limit. With power comes responsibility.
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Summaries
‘Ancestry problem’ Sends CRISPR Astray in Some People
Reference genomes used to direct the gene editor fail to account for human diversity in those of African descent
Science, 2022
Landmark CRISPR Trial Shows Promise Against Deadly Disease
Administering gene-editing treatment directly into the body could be a safe and effective way to treat a rare, life-threatening condition.
Nature, 2021
A Crack in Creation
Gene Editing and the Unthinkable Power to Control Evolution
Houghton Mifflin Harcourt, 2017
Gene Therapy Tackles a Common Birth Defect: Deafness
After false starts, researchers are making progress toward treating deafness with gene therapy
Scientific American, 2018
Could the Next Big Information Technology Be ... DNA?
How DNA is used to store – and generate – information at extreme scales
Scientific American, 2019
A Brief History of Everyone Who Ever Lived
The Human Story Retold Through Our Genes
Experiment, 2017
China’s CRISPR Revolution
Editing of plant, animal and human genomes has never been easier, as this country’s scientists are rapidly demonstrating.
Science, 2019
What’s Next for CRISPR Babies?
Following last year’s bombshell revelation, investigations mount and debates swirl about the future for gene-edited humans. Here are the four most pressing questions.
Nature, 2019