It takes a long way for a pharmaceutical drug to be available to patients who use them as medications. The process begins with drug discovery and is followed by drug development, production and marketing. It’s regulated and often requires extensive testing for safety and efficacy, involving clinical trials.
Hope, Justice, and the Future of America’s Overdose Crisis
Little, Brown US, 2022
Freakonomics Radio, 2022
Inside Pfizer's Nine-Month Race to Make the Impossible Possible
Empire of Pain
The Secret History of the Sackler Dynasty
The True Tale of America's Opiate Epidemic
Bloomsbury Press, 2016
An AI Tool to Make Clinical Trials More Inclusive
An artificial-intelligence tool called Trial Pathfinder can run clinical-trial emulations using healthcare data from people with cancer, and can learn how to optimize trial-inclusion eligibility criteria, while maintaining patient safety.
Chronotherapy – the specific timing of drug delivery – has shown promise in clinical trials. But that may not be enough to overcome the practical challenges.
The Hard Sell
Crime and Punishment at an Opioid Startup
Boston Consulting Group, 2020