Summary of Biologist Explains One Concept in 5 Levels of Difficulty – CRISPR

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Biologist Explains One Concept in 5 Levels of Difficulty – CRISPR summary
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Genetic editing has been around for decades, but CRISPR technology has scientists dreaming up new experiments. This gene editing system can specifically modify the genome of various species including our own. While some have raised ethical concerns, researchers are only slowly beginning to understand the strengths and weaknesses of the CRISPR system. In the future, doctors could treat diseases with this new technology and usher in a new field of medicine. getAbstract recommends this article to those interested in exciting new trends in genetics and medicine.

In this summary, you will learn

  • What CRISPR technology is,
  • How scientists currently use CRISPR in the lab and
  • How future medicines could use CRISPR to treat human diseases.
 

About the Speaker

Dr. Neville Sanjana is a biologist at New York University and the New York Genome Center. His work has been published in journals such as Nature and Science.

 

Summary

CRISPR is a gene editing technology able to target and edit specific regions in the genome.

CRISPR is not the first genetic editing technology, however it is more specific than previous technologies. Researchers first identified the system in bacteria as a protein complex known as the Cas9 complex. Scientists can use Cas9 together with a designed guide RNA to target precise regions of the genome. Variants of the CRISPR system exist in different bacterial species, which expands the scientific toolbox for researchers. For example, there are CRISPR systems that are better suited to target different regions of the genome and there is a CRISPR system that targets RNA instead of DNA, allowing scientists to regulate protein expression at different levels.


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